Neuroscience • Interoception • Mental Health
Exploring how the nervous system senses the body and how internal signals shape emotion, development, and health.

This line of work aims to understand how early-life adversity (ELA) impacts individual differences in interoception, and how these differences may underlie risk for mental and physical health.
Our recent theoretical work suggests that the physiological, hormonal, and neural changes of pregnancy may make it a sensitive period for interoceptive functions. We suggest interoception may be heightened during pregnancy to adapt to the physiological and metabolic challenges — as supported by our online self-reported data and in-lab task based measures of interoception.
Building on our findings linking pregnancy and interoception, we have extended our work to specifically focus on how hormonal fluctuations may impact both self-reported and task-based measures of interoception. The Cyclic Hormones and Interoception with Repeated Profiling (CHIRP) study is a longitudinal dense sampling study to examine how natural fluctuations across the menstrual cycle interaction with self-report, task-based, and neural measures of interoception.
Exploring the relationships between discrimination, alexithymia, and anxiety in women.
PW Savoca, A Fabian, SM Esfand, BL Callaghan
Stigma and Health (2025)
Exploring the impact of maternal early life adversity on interoceptive sensibility in pregnancy: implications for prenatal depression
PW Savoca, LM Glynn, MM Fox, MC Richards, BL Callaghan
Archives of Women’s Mental Health (2025)
Interoception in pregnancy: Implications for peripartum depression
PW Savoca, LM Glynn, MM Fox, MC Richards, BL Callaghan
Neuroscience & Biobehavioral Reviews (2024)